Биохимические изменения у крыс после употребления газированного напитка и ментоловых конфет

В текущем исследовании изучались биохимические изменения, имевшие место у крыс после того, как им давали ментоловые конфеты и газированный напиток. Всего было получено семьдесят самцов крыс-альбиносов породы Вистар, разделенных на десять групп по семь крыс в каждой. Эксперимент проводился по описанной ниже схеме в течение сорока двух дней. Группа 1 — контрольная. Группы 2, 3 и 4 получали 8, 5 и 2,5 мл напитка «La Casera»/кг веса. Группы 5, 6 и 7 получали 0,34, 0,22 и 0,11 г конфет «Tom-Tom»/кг веса. Дозировки для групп 8, 9 и 10 составляли 8, 5 и 2,5 мл напитка «La Casera»/кг веса, а также 0,34, 0,22 и 0,11 г конфет «Tom-Tom»/кг веса, соответственно. Результаты показали, что в сыворотке крови у крыс, которым давали «Tom-Tom» и «La Casera», наблюдались более низкие уровни общего белка (TP) и альбумина (Alb), и значительно (p < 0,05) более высокие уровни аланинаминотрансферазы (ALT), аспартатами- нотрансферазы (AST), щелочной фосфатазы (ALP), общего холестерина (T-Chol), триглицеридов (TAG) и холестерина липопротеинов низкой плотности (LDL–C). Кроме того, между группами 7 и 5 наблюдалось существенное (p < 0,05) увеличение сывороточных уровней TP, Alb и ALT. Вследствие пагубных изменений в биохимических параметрах и во избежание отрицательных последствий для здоровья следует избегать длительного употребления конфет «Tom-Tom» совместно с напитком «La Casera».

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