Preview

Пищевые системы

Расширенный поиск

Биологически активные вещества бузины: свойства, методы извлечения и сохранения

https://doi.org/10.21323/2618-9771-2023-6-1-80-94

Аннотация

Антоцианы и полифенолы являются основными биологически активными веществами, содержащимися в  ягодах бузины. Методы экстракции оказывают существенное влияние на эффективность извлечения, биодоступность и сохранение биологически активных соединений. Цель данной работы — обзор опубликованных результатов научных исследований бузины и продуктов ее переработки, их воздействия на организм, а также рассмотрение методов извлечения и инкапсуляции биологически активных соединений бузины. В обзор включены статьи на английском и русском языках. Поиск зарубежной научной литературы на английском языке по данной теме проводили в библиографических базах Google Scholar, Scopus, Web of Science, Elsevier, ResearchGate. Для отбора научных статей на русском языке провели поиск по ключевым словам в «Научной электронной библиотеке eLIBRARY.RU». Обзор научных публикаций показал, что результаты многочисленных исследований подтверждают высокую антиоксидантную активность бузины (Sambucus nigra L.), а также дикой бузины (Sambucus ebulus), произрастающей на территории Республики Беларусь, а также в других странах Европы, Азии, Северной Африки и Северной Америки. Благодаря наличию в химическом составе бузины (Sambucus nigra L.) биоактивных флавоноидов, таких как кверцетин, кемпферол и рутин, а также за счет присутствия других фенольных соединений, это растение используется в традиционной медицине и  применяется в  качестве сырья в  пищевой промышленности для создания продуктов профилактического и  функционального назначения. Биоактивные соединения бузины обладают некоторыми уникальными биологическими и  фармакологическими свойствами, включая антиоксидантную, противоопухолевую, антидепрессивную, антидиабетическую, противовирусную и антибактериальную активность. Для извлечения биоактивных веществ из ягод бузины используются традиционные методы экстракции, такие как мацерация и  экстракция Сокслета, а также современные перспективные «зеленые» технологии: сверхкритические флюиды, импульсное электрическое поле, экстракция жидкой эмульсии, микроволновая и ультразвуковая экстракция. Для сохранения и защиты биологически активных веществ, содержащихся в плодах бузины, применяются методы инкапсуляции, являющиеся наиболее эффективными. Материалы данной статьи могут быть использованы при проведении дальнейших исследований по оптимизации процессов экстракции с целью повышения пищевой ценности и антиоксидантной активности новых функциональных продуктов питания, пищевых добавок, а также продуктов фармацевтической промышленности.

Об авторах

Л. Ч. Бурак
Общество с ограниченной ответственностью «БЕЛРОСАКВА»
Беларусь

Бурак Леонид Чеславович  — кандидат технических наук, директор

220118, Минск, ул. Шаранговича, 19, офис 718

Tел.: +37517–379–51–61



А. Н. Сапач
Общество с ограниченной ответственностью «БЕЛРОСАКВА»
Беларусь

Сапач Александр Николаевич — инженер-химик

220118, Минск, ул. Шаранговича, 19, офис 718

Tел.: +37517–379–51–61



Список литературы

1. Waźbińska, J. (2002). Sambucus for growers. Szkółkarstwo, 6, 29–30. (In Polish)

2. Vujanović, M., Majkić, T., Zengin, G., Beara, I., Cvetanović, A., Mahomoodally, F. M. et al. (2019). Advantages of contemporary extraction techniques for the extraction of bioactive constituents from black elderberry (Sambucus nigra L.) flowers. Industrial Crops and Products, 136, 93–101. https://doi.org/10.1016/j.indcrop.2019.04.058

3. Gomez Mattson, M. L., Corfield, R., Bajda, L., Pérez, O.E., Schebor, C., Salvatori, D. (2021). Potential bioactive ingredient from elderberry fruit: Process optimization for a maximum phenolic recovery, physicochemical characterization, and bioaccesibility. Journal of Berry Research, 11(1), 51–68. https //doi.org/10.3233/JBR‑200629

4. Młynarczyk, K., Walkowiak-Tomczak, D., Łysiak, G.P. (2018). Bioactive properties of Sambucus nigra L. As a functional ingredient for food and pharmaceutical industry. Journal of Functional Foods, 40, 377–390. https://doi.org/10.1016/j.jff.2017.11.025

5. Młynarczyk, K., Walkowiak-Tomczak, D., Staniek, H., Kidoń, M., Łysiak, G.P. (2020). The Content of selected minerals, bioactive compounds, and the antioxidant properties of the flowers and fruit of selected cultivars and wildly growing plants of Sambucus nigra L. Molecules, 25, Article 876. https://doi.org/10.3390/molecules25040876

6. Бурак, Л. Ч. (2022). Использование бузины (Sambucus nigra L.) в пищевой промышленности: состояние и дальнейшие перспективы (Обзор). Химия растительного сырья, 3, 49–69. https://doi.org/10.14258/jcprm.20220310937

7. Бурак, Л. Ч., Завалей, А.П. (2021). Технологический процесс производства и оценка качества сока прямого отжима и концентрированного из плодов бузины произрастающей в Республике Беларусь. Пищевая промышленность, 11, 83–87. https://doi.org/10.52653/PPI.2021.11.11.001

8. Abdel-Moneim, A.-M. E., Shehata, A.M., Alzahrani, S.O., Shafi, M.E., Mesalam, N.M., Taha, A.E. et al. (2020). The role of polyphenols in poultry nutrition. Journal of Animal Physiology and Animal Nutrition, 104(6), 1851–1866. https://doi.org/10.1111/jpn.13455

9. Garavand, F., Madadlou, A., Moini, S. (2017). Determination of phenolic profile and antioxidant activity of pistachio hull using high-performance liquid chromatography-diode array detectorelectro-spray ionization — mass spectrometry as affected by ultrasound and microwave. International Journal of Food Properties, 20(1), 19–29. https://doi.org/10.1080/110942912.2015.1099045

10. Garavand, F., Rahaee, S., Vahedikia, N., Jafari, S.M. (2019). Different techniques for extraction and micro/nanoencapsulation of saffron bioactive ingredients. Trends in Food Science and Technology, 89, 26–44. https://doi.org/10.1016/j.tifs.2019.05.005

11. Sobieralska, M., Kurek, M.A. (2019). Beta-glucan as wall material in encapsulation of elderberry (Sambucus nigra) extract. Plant Foods for Human Nutrition, 74(3), 334–341. https://doi.org/10.1007/s11130–019–00741-x

12. Paz, R., Fredes, C. (2015). The encapsulation of anthocyanins from berry-type fruits. Trends in foods. Molecules, 20(4), 5875–5888. https://doi.org/10.3390/molecules20045875

13. Moghaddam, M. H., Bayat, A.-H., Eskandari, N., Abdollahifar, M.-A., Fotouhi, F., Forouzannia, A. et al. (2021). Elderberry diet ameliorates motor function and prevents oxidative stress-induced cell death in rat models of Huntington disease. Brain Research, 1762, Article 147444. https://doi.org/10.1016/j.brainres.2021.147444

14. Mesalam, N.M., Aldhumri, S.A., Gabr, S.A., Ibrahim, M.A., Al-Mokaddem, A.K., Abdel-Moneim, A.-M.E. (2021). Putative abrogation impacts of Ajwa seeds on oxidative damage, liver dysfunction and associated complications in rats exposed to carbon tetrachloride. Molecular Biology Reports, 48(6), 5305–5318. https://doi.org/10.1007/s11033–021–06544–1

15. Vujanovíc, M., Majkíc, T., Zengin, G., Beara, I., Tomovíc, V., Šojić, B. et al. (2020). Elderberry (Sambucus nigra L.) juice as a novel functional product rich in health-promoting compounds. RSC Advances, 10, 44805–44814. https://doi.org/10.1039/d0ra09129d

16. Senica, M., Stampar, F., Veberic, R., Mikulic-Petkovsek, M. (2017). The higher the better? Differences in phenolics and cyanogenic glycosides in Sambucus nigra leaves, flowers and berries from different altitudes. Journal of the Science of Food and Agriculture, 97(8), 2623–2632. https://doi.org/10.1002/jsfa.8085

17. Aliakbarian, B., Paini, M., Casazza, A.A., Perego, P. (2015). Effect of encapsulating agent on physical-chemical characteristics of olive pomace polyphenols-rich extracts. Chemical Engineering Transactions, 43, 97–102. https://doi.org/10.3303/cet1543017

18. Đorđević, V., Balanč, B., Belščak-Cvitanović, A., Lević, S., Trifković, K., Kalušević, A. et al. (2015). Trends in encapsulation technologies for delivery of food bioactive compounds. Food Engineering Reviews, 7(4), 452– 490. https://doi.org/10.1007/s12393–014–9106–7

19. Bakowska-Barczak, A. M., Kolodziejczyk, P. P. (2011). Black currant polyphenols: Their storage stability and microencapsulation. Industrial Crops and Products, 34(2), 1301–1309. https://doi.org/10.1016/j.indcrop.2010.10.002

20. Aguiar, J., Estevinho, B. N., Santos, L. (2016). Microencapsulation of natural antioxidants for food application — The specific case of coffee antioxidants — A review. Trends in Food Science and Technology, 58, 21–39. https://doi.org/10.1016/j.tifs.2016.10.012

21. Wahab, N. A., Rahman, R.A, Ismail, A., Mustafa, S., Hashim, P. (2014). Assessment of antioxidant capacity, anti-collagenase and anti-elastase assays of Malaysian unfermented cocoa bean for cosmetic application. Natural Products Chemistry and Research, 2(3), Article 1000132. https://doi.org/10.4172/2329–6836.1000132

22. Ghimeray, A. K., Jung, U., Lee, H., Kim, Y., Ryu, E., Chang, M. (2015). In vitro antioxidant, collagenase inhibition, and in vivo anti-wrinkle effects of combined formulation containing Punica granatum, Ginkgo biloba, Ficus carica, and Morus alba fruits extract. Clinical, Cosmetic and Investigational Dermatology, 8, 389–396. https://doi.org/10.2147/CCID.S80906

23. Perše, M. (2013). Oxidative stress in the pathogenesis of colorectal cancer: cause or consequence? BioMed Research International, 2013, Article 725710. https://doi.org/10.1155/2013/725710

24. Olejnik, A., Olkowicz, M., Kowalska, K., Rychlik, J., Dembczyński, R., Myszka, K. et al. (2016). Gastrointestinal digested Sambucus nigra L. fruit extract protects in vitro cultured human colon cells against oxidative stress. Food Chemistry, 197(Part A), 648–657. https://doi.org/10.1016/j.foodchem.2015.11.017

25. Sidor, A., Gramza-Michałowska, A. (2015). Advanced research on the antioxidant and health benefit of elderberry (Sambucus nigra) in food–a review. Journal of Functional Foods, 18(Part B), 941–958. https://doi.org/10.1016/j.jff.2014.07.012

26. Hidalgo, M., Oruna-Concha, M.J., Kolida, S., Walton, G.E., Kallithraka, S., Jeremy P. E. Spencer, J.P.E. et al. (2012). Metabolism of anthocyanins by human gut microflora and their influence on gut bacterial growth. Journal of Agricultural and Food Chemistry, 60(15), 3882–3890. https://doi.org/10.1021/jf3002153

27. Lila, M. A., Ribnicky, D.M., Rojo, L.E., Rojas-Silva, P., Oren, A., Havenaar, R., Janle, E.M. et al. (2012). Complementary approaches to gauge the bioavailability and distribution of ingested berry polyphenolics. Journal of Agricultural and Food Chemistry, 60(23), 5763–5771. https://doi.org/10.1021/jf203526h

28. Olejnik A., Kowalska, K., Olkowicz, M., Rychlik, J., Juzwa, W., Myszka, K. et al. (2015). Anti-inflammatory effects of gastrointestinal digested Sambucus nigra L. fruit extract analysed in co-cultured intestinal epithelial cells and lipopolysaccharide-stimulated macrophages. Journal of Functional Foods, 19(Part A), 649–660. https://doi.org/10.1016/j.jff.2015.09.064

29. Frøkiær, H., Henningsen, L., Metzdorff, B.S., Weiss, G., Roller, M., Flanagan, J. et al. (2012). Astragalus root and elderberry fruit extracts enhance the IFN‑β stimulatory effects of Lactobacillus acidophilus in murine-derived dendritic cells. PLoS One, 7(10), Article e47878. https://doi.org/10.1371/journal.pone.0047878

30. Pliszka, B., Wazbinska, J., Puczel, U., Huszcza-Ciołkowska, G. (2005). Biologically active polyphenolic compounds in elderberries of different cultivated varieties and wild-growing forms. Zeszyty Problemowe Postępów Nauk Rolniczych, 507(2), 443–449. (In Polish)

31. Przybylska-Balcerek, A., Szablewski, T., Szwajkowska-Michałek, L., Świerk, D., Cegielska-Radziejewska, R., Krejpcio, Z. et al. (2021). Sambucus nigra extracts — Natural antioxidants and antimicrobial compounds. Molecules, 26(10), Article 2910. https://doi.org/10.3390/molecules26102910

32. Boroduske, A., Jekabsons, K., Riekstina, U., Muceniece, R., Rostoks, N., Nakurte, I. (2021). Wild Sambucus nigra L. from north-east edge of the species range: A valuable germplasm with inhibitory capacity against SARS-CoV2 S‑protein RBD and hACE2 binding in vitro. Industrial Crops and Products, 165, Article 113438. https://doi.org/10.1016/j.indcrop.2021.113438

33. Gleńsk, M., Gliński, J.A., Włodarczyk, M., Stefanowicz, P. (2014). Determination of ursolic and oleanolic acid in Sambuci fructus. Chemistry and Biodiversity, 11(12), 1939–1944. https://doi.org/10.1002/cbdv.201400118

34. Caroline, H., Mccollum, G.A., Nelson, D., Ballard, L.M., Millar, C., Goldsmith, C. et al. (2010). Antibacterial activity of elder (Sambucus nigra L.) flower or berry against hospital pathogens. Journal of Medicinal Plants Research, 4(17), 1805–1809. https://doi.org/10.5897/JMPR10.147

35. Chatterjee, A., Yasmin, T., Bagchi, D., Stohs, S.J. (2004). Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycin. Molecular and Cellular Biochemistry, 265(1–2), 19–26. https://doi.org/10.1023/B:MCBI.0000044310.92444.ec

36. Krawitz, C., Mraheil, M.A., Stein, M., Imirzalioglu, C., Domann, E., Pleschka, S. et al. (2011). Inhibitory activity of a standardized elderberry liquid extract against clinically-relevant human respiratory bacterial pathogens and influenza A and B viruses. BMC Complementary and Alternative Medicine, 11(1), Article 16. https://doi.org/10.1186/1472–6882–11–16

37. Chen, C., Zuckerman, D.M., Susanna Brantley, Michka Sharpe, Kevin Childress, Egbert Hoiczyk, et al. (2014). Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication. BMC Veterinary Research, 10(1), Article 24. https://doi.org/10.1186/1746–6148–10–24

38. Roschek, Jr. B., Fink, R.C., McMichael, M.D., Li, D., Alberte, R.S. (2009). Elderberry flavonoids bind to and prevent H1N1 infection in vitro. Phytochemistry, 70(10), 1255–1261. https://doi.org/10.1016/j.phytochem.2009.06.003

39. Hawkins, J., Baker, C., Cherry, L., Dunne, E. (2019). Black elderberry (Sambucus nigra) supplementation effectively treats upper respiratory symptoms: A meta-analysis of randomized, controlled clinical trials. Complementary Therapies in Medicine, 42, 361–365. https://doi.org/10.1016/j.ctim.2018.12.004

40. Tiralongo, E., Wee, S. S., Lea, R. A. (2016). Elderberry supplementation reduces cold duration and symptoms in air-travellers: A randomized, double-blind placebo-controlled clinical trial. Nutrients, 8(4), Article 182. https://doi.org/10.3390/nu8040182

41. Zakay-Rones, Z., Varsano, N., Zlotnik, M., Manor, O., Regev, L., Schlesinger, M. et al. (1995). Inhibition of several strains of influenza virus in vitro and reduction of symptoms by an elderberry extract (Sambucus nigra L.) during an outbreak of influenza B Panama. The Journal of Alternative and Complementary Medicine, 1(4), 361–369. https://doi.org/10.1089/acm.1995.1.361

42. Kinoshita, E., Hayashi, K., Katayama, H., Hayashi, T., Obata, A. (2012). Anti-influenza virus effects of elderberry juice and its fractions. Bioscience, Biotechnology, and Biochemistry, 76(9), 1633–1639. https://doi.org/10.1271/bbb.120112

43. Hidari, K. I. P. J., Abe, T., Suzuki, T. (2013). Crabohydrate — related inhibitors of dengue virus entry. Viruses, 5(2), 605–618. https://doi.org/10.3390/v5020605

44. McCutcheon, A. R., Roberts, T.E., Gibbons, E., Ellis, S.M., Babiuk, L.A., Hancock, R.E. et al. (1995). Antiviral screening of British Columbian medicinal plants. Journal of Ethnopharmacology, 49(2), 101–110. https://doi.org/10.1016/0378–8741(95)90037–3

45. Van der Meer, F., de Haan, C.A.M., Schuurman, N.M.P., Haijema, B.J., Verheije, M.H., Bosch, B.J. et al. (2007). The carbohydrate-binding plant lectins and the non-peptidic antibiotic pradimicin A target the glycans of the coronavirus envelope glycoproteins. Journal of Antimicrobial Chemotherapy, 60(4), 741–749. https://doi.org/10.1093/jac/dkm301

46. Graham, D. R. M., Chertova, E., Hilburn, J.M., Arthur, L.O., Hildreth, J.E.K. (2003). Cholesterol depletion of human immunodeficiency virus type 1 and simian immunodeficiency virus with beta-cyclodextrin inactivates and permeabilizes the virions: evidence for virion-associated lipid rafts. Journal of Virology, 77(15), 8237–8248. https://doi.org/10.1128/jvi.77.15.8237–8248.2003

47. Bartak, M., Lange, A., Słońska, A., Cymerys, J. (2020). Antiviral and healing potential of Sambucus nigra extracts. Revista Bionatura, 5(3), 1264–1270. http://dx.doi.org/10.21931/RB/2020.05.03.18

48. Rechenchoski, D. Z., Faccin-Galhardi, L.C., Linhares, R.E.C., Nozawa, C. (2017). Herpesvirus: an underestimated virus. Folia Microbiologica (Praha), 62(2), 151–156. https://doi.org/10.1007/s12223–016–0482–7

49. Harnett, J., Oakes, K., Carè, J., Leach, M., Brown, D., Cramer, H. et al. (2020). The effects of Sambucus nigra berry on acute respiratory viral infections: A rapid review of clinical studies. Advances in Integrative Medicine, 7(4), 240–246. https://doi.org/10.1016/j.aimed.2020.08.001

50. Kronbichler, A., Effenberger, M., Eisenhut, M., Lee, K.H., Shin, J.I. (2020). Seven recommendations to rescue the patients and reduce the mortality from COVID‑19 infection: An immunological point of view. Autoimmunity Reviews, 19(7), Article 102570. https://doi.org/10.1016/j.autrev.2020.102570

51. Silveira, D., Prieto-Garcia, J.M., Boylan, F., Estrada, O., Fonseca-Bazzo, Y.M., Jamal, C.M. et al. (2020). COVID‑19: is there evidence for the use of herbal medicines as adjuvant symptomatic therapy? Frontiers in Pharmacology, 11, Article 581840. 1479. https://doi.org/10.3389/fphar.2020.581840

52. Ho, G. T. T., Kase, E.T., Wangensteen, H., Barsett, H. (2017). Phenolic elderberry extracts, anthocyanins, procyanidins, and metabolites influence glucose and fatty acid uptake in human skeletal muscle cells. Journal of Agricultural and Food Chemistry, 65(13), 2677–2685. https://doi.org/10.1021/acs.jafc.6b05582

53. Manna, P., Jain, S. K. (2015). Obesity, oxidative stress, adipose tissue dysfunction, and the associated health risks: causes and therapeutic strategies. Metabolic Syndrome and Related Disorders, 13(10), 423–444. https://doi.org/10.1089/met.2015.0095

54. Matsuda, M., Shimomura, I. (2013). Increased oxidative stress in obesity: implications for metabolic syndrome, diabetes, hypertension, dyslipidemia, atherosclerosis, and cancer. Obesity Research and Clinical Practice, 7(5), e330-e341. https://doi.org/10.1016/j.orcp.2013.05.004

55. Zielińska-Wasielica, J., Olejnik, A., Kowalska, K., Olkowicz, M., Dembczyński, R. (2019). Elderberry (Sambucus nigra L.) fruit extract alleviates oxidative stress, insulin resistance, and inflammation in hypertrophied 3T3-L1 adipocytes and activated RAW 264.7 macrophages. Foods, 8(8), Article 326. https://doi.org/10.3390/foods8080326

56. Farrell, N. J., Norris, G.H., Ryan, J., Porter, C.M., Jiang, C., Blesso, C.N. (2015). Black elderberry extract attenuates inflammation and metabolic dysfunction in diet-induced obese mice. British Journal of Nutrition, 114(8), 1123–1131. https://doi.org/10.1017/S0007114515002962

57. Salvador, Â. C., Król, E., Lemos, V.C., Santos, S.A.O., Bento, F.P.M.S., Costa, C.P., Almeida, A. et al. (2016). Effect of elderberry (Sambucus nigra L.) extract supplementation in STZ‑induced diabetic rats fed with a high-fat diet. International Journal of Molecular Sciences, 18(1), Article 13. https://doi.org/10.3390/ijms18010013

58. Farrell, N., Norris, G., Lee, S.G., Chun, O.K., Blesso, C.N. (2015). Anthocyanin-rich black elderberry extract improves markers of HDL function and reduces aortic cholesterol in hyperlipidemic mice. Food and Function, 6(4), 1278–1287. https://doi.org/10.1039/c4fo01036a

59. Opris, R., Tatomir, C., Olteanu, D., Moldovan, R., Moldovan, B., David, L. et al. (2017). The effect of Sambucus nigra L. extract and phytosinthesized gold nanoparticles on diabetic rats. Colloids and Surfaces B: Biointerfaces, 150, 192–200. https://doi.org/10.1016/j.colsurfb.2016.11.033

60. Karthick, V., Kumar, V.G., Dhas, T.S., Singaravelu, G., Sadiq, A.M., Govindaraju, K. (2014). Effect of biologically synthesized gold nanoparticles on alloxan-induced diabetic rats — an in vivo approach. Colloids and Surfaces B: Biointerfaces, 122, 505–511. https://doi.org/10.1016/j.colsurfb.2014.07.022

61. Badescu, L., Badulescu, O., Badescu, M., Ciocoiu, M. (2012). Mechanism by Sambucus nigra extract improves bone mineral density in experimental diabetes. Evidence-based Complementary and Alternative Medicine, 2012, Article 848269. https://doi.org/10.1155/2012/848269

62. Cutrim, C. S., de Barrosa, R.F., da Costa, P.M., Franco, R.M., Conte-Junior, C.A., Cortez, M.A.S. (2016). Survival of Escherichia coli O157: H7 during manufacture and storage of traditional and low lactose yogurt. LWT, 70, 178–184. https://doi.org/10.1016/j.lwt.2016.02.047

63. Mattila, P., Kumpulainen, J. (2002). Determination of free and total phenolic acids in plant-derived foods by HPLC with diode-array detection. Journal of Agricultural and Food Chemistry, 50 (13), 3660–3667. https://doi.org/10.1021/jf020028p

64. Stanković, M., Maksimović, S., Tadić, V., Arsić, I. (2018). The oil content of wild fruits from different plant species obtained by conventional Soxhlet extraction technique. Acta Facultatis Medicae Naissensis, 35(3), 193–199. https://doi.org/10.2478/afmnai‑2018–0021

65. Kowalska, G., Wyrostek, J., Kowalski, R., Pankiewicz, U. (2021). Evaluation of glycerol usage for the extraction of anthocyanins from black chokeberry and elderberry fruit. Journal of Applied Research on Medicinal and Aromatic Plants, 22, Article 100296. https://doi.org/10.1016/j.jarmap.2021.100296

66. Gullón, B., Lú-Chau, T.A., Moreira, M.T., Lema, J.M., Eibes, G. (2017). Rutin: A review on extraction, identification and purification methods, biological activities and approaches to enhance its bioavailability. Trends in Food Science and Technology, 67, 220–235. https://doi.org/10.1016/j.tifs.2017.07.008

67. Suwal, S., Marciniak, A. (2018). Technologies for the extraction, separation and purification of polyphenols — A Review. Nepal Journal of Biotechnology, 6(1), 74–91. https://doi.org/10.3126/njb.v6i1.22341

68. Domínguez, R., Zhang, L., Rocchetti, G., Lucini, L., Pateiro, M., Munekata, P.E.S. et al. (2020). Elderberry (Sambucus nigra L.) as potential source of antioxidants. Characterization, optimization of extraction parameters and bioactive properties. Food Chemistry, 330, Article 127266. https://doi.org/10.1016/j.foodchem.2020.127266

69. Salvador, Â. C., Rocha, S.M., Silvestre, A.J.D. (2015). Lipophilic phytochemicals from elderberries (Sambucus nigra L.): Influence of ripening, cultivar and season. Industrial Crops and Products, 71, 15–23. https://doi.org/10.1016/j.indcrop.2015.03.082

70. El Asbahani, A., Miladi, K., Badri, W., Sala, M., Addi, E.H.A., Casabianca, H. et al. (2015). Essential oils: From extraction to encapsulation. International Journal of Pharmaceutics, 483(1–2), 220–43. https://doi.org/10.1016/j.ijpharm.2014.12.069

71. Ağalar, H. G., Demirci, B., Demirci, F., Kırımer, N. (2017). The volatile compounds of the elderflowers extract and the essential oil. Records of Natural Products, 11(5), 491–496. http://doi.org/10.25135/rnp.63.16.08.058

72. Ali Redha, A., Siddiqui, S.A., Ibrahim, S.A. (2021). Advanced extraction techniques for Berberis species phytochemicals: A review. International Journal of Food Science and Technology, 56(11), 5485–5496. https://doi.org/10.1111/ijfs.15315

73. Belwal, T., Bhatt, I.D., Rawal, R.S., Pande, V. (2017). Microwave-assisted extraction (MAE) conditions using polynomial design for improving antioxidant phytochemicals in Berberis asiatica Roxb. ex DC. leaves. Industrial Crops and Products, 95, 393–403. https://doi.org/10.1016/j.indcrop.2016.10.049

74. Mota, A. H., Andrade, J.M., Ntungwe, E.N., Pereira, P., Cebola, M.J., Bernardo-Gil, M.G. et al. (2020). Green extraction of Sambucus nigra L. for potential application in skin nanocarriers. Green Materials, 8(4), 181–193. https://doi.org/10.1680/jgrma.18.00074

75. Wen, L., Zhang, Z., Sun, D.-W., Sivagnanam, S.P., Tiwari, B.K. (2020). Combination of emerging technologies for the extraction of bioactive compounds. Critical Reviews in Food Science and Nutrition, 60(11), 1826–1841. https://doi.org/10.1080/10408398.2019.1602823

76. Rodríguez Madrera, R., Suárez Valles, B. (2021). Analysis of cyanogenic compounds derived from mandelonitrile by ultrasound-assisted extraction and high-performance liquid chromatography in Rosaceae and Sambucus families. Molecules, 26(24), Article 7563. https://doi.org/10.3390/molecules26247563

77. Zhu, Z., Chen, Z., Zhou, Q., Sun, D.-W., Chen, H., Zhao, Y. et al. (2018). Freezing efficiency and quality attributes as affected by voids in plant tissues during ultrasound-assisted immersion freezing. Food and Bioprocess Technology, 11(9), 1615–1626. https://doi.org/10.1007/s11947–018–2103–8

78. Zhu, Z., Sun, D.-W., Zhang, Z., Li, Y., Cheng, L. (2018). Effects of micronano bubbles on the nucleation and crystal growth of sucrose and maltodextrin solutions during ultrasound-assisted freezing process. LWT, 92, 404–411. https://doi.org/10.1016/j.lwt.2018.02.053

79. Kitrytė, V., Povilaitis, D., Kraujalienė, V., Šulniūtė, V., Pukalskas, A., Venskutonis, P.R. (2017). Fractionation of sea buckthorn pomace and seeds into valuable components by using high pressure and enzyme-assisted extraction methods. LWT — Food Science and Technology, 85(Part B), 534–538. https://doi.org/10.1016/j.lwt.2017.02.041

80. Kitrytė, V., Laurinavičienė, A., Syrpas, M., Pukalskas, A., Venskutonis, P.R. (2020). Modeling and optimization of supercritical carbon dioxide extraction for isolation of valuable lipophilic constituents from elderberry (Sambucus nigra L.) pomace. Journal of CO2 Utilization, 35, 225–235. https://doi.org/10.1016/j.jcou.2019.09.020

81. Nadar, S. S., Rao, P., Rathod, V.K. (2018). Enzyme assisted extraction of biomolecules as an approach to novel extraction technology: A review. Food Research International, 108, 309–330. https://doi.org/10.1016/j.foodres.2018.03.006

82. Flores, E. (2017). Antioxidant extraction from elderberries (Sambucus nigra L. Subsp. peruviana) with ultrasound, microwave, enzymes, and maceration to obtain functional juices Informacion Tecnologica, 28(1), 121–132. http://doi.org/10.4067/S0718–07642017000100012 (In Spanish)

83. Tamkutė, L., Liepuoniūtė, R., Pukalskienė, M., Venskutonis, P.R. (2020). Recovery of valuable lipophilic and polyphenolic fractions from cranberry pomace by consecutive supercritical CO2 and pressurized liquid extraction. The Journal of Supercritical Fluids, 159, Article 104755. https://doi.org/10.1016/j.supflu.2020.104755

84. Carvalho, I. T., Estevinho, B.N., Santos, L. (2016). Application of microencapsulated essential oils in cosmetic and personal healthcare products — a review. International Journal of Cosmetic Science, 3(2), 109–119. https://doi.org/10.1111/ics.12232

85. Estevinho, B. N., Carlan, I., Blaga, A., Rocha, F. (2016). Soluble vitamins (vitamin B12 and vitamin C) microencapsulated with different biopolymers by a spray drying process. Powder Technology, 289, 71–78. https://doi.org/10.1016/j.powtec.2015.11.019

86. Gonçalves, A., Estevinho, B.N., Rocha, F. (2016). Microencapsulation of vitamin A: A review. Trends in Food Science and Technology, 51, 76–87. https://doi.org/10.1016/j.tifs.2016.03.001

87. Comunian, T. A., Ravanfar, R., Alcaine, S.D., Abbaspourrad, A. (2018). Water-in-oil-in-water emulsion obtained by glass microfluidic device for protection and heat-triggered release of natural pigments. Food Research International, 10, 945–951. https://doi.org/10.1016/j.foodres.2018.02.008

88. Kanha, N., Regenstein, J.M., Surawang, S., Pitchakarn, P., Laokuldilok, T. (2021). Properties and kinetics of the in vitro release of anthocyaninrich microcapsules produced through spray and freeze-drying complex coacervated double emulsions. Food Chemistry, 340, Article 127950. https://doi.org/10.1016/j.foodchem.2020.127950

89. Casati, C. B., Baeza, R., Sánchez, V. (2019). Physicochemical properties and bioactive compounds content in encapsulated freeze-dried powders obtained from blueberry, elderberry, blackcurrant and maqui berry. Journal of Berry Research, 9(3), 431–447. https://doi.org/10.3233/JBR‑190409


Рецензия

Для цитирования:


Бурак Л.Ч., Сапач А.Н. Биологически активные вещества бузины: свойства, методы извлечения и сохранения. Пищевые системы. 2023;6(1):80-94. https://doi.org/10.21323/2618-9771-2023-6-1-80-94

For citation:


Burak L.Ch., Sapach A.N. Biologically active substances of elder: Properties, methods of extraction and preservation. Food systems. 2023;6(1):80-94. (In Russ.) https://doi.org/10.21323/2618-9771-2023-6-1-80-94

Просмотров: 743


Creative Commons License
Контент доступен под лицензией Creative Commons Attribution 4.0 License.


ISSN 2618-9771 (Print)
ISSN 2618-7272 (Online)