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IFLUENCE OF FUNCTIONAL FOOD PRODUCT ON SERUM FATTY ACID COMPOSITION IN HYPERLIPIDEMIC RATS

https://doi.org/10.21323/2618-9771-2018-1-4-4-9

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Abstract

A special area in the rapidly growing range of food products is occupied by specialized and functional products, especially for certain categories of citizens. In addition to confirming their biocorrective properties, it’s necessary to balance protein, fat and carbohydrates contents as well as the availability of essential nutrients. The developed meat product based on porcine hearts and aorta was characterized by a high protein content (17.53±0.95%), with a low fat content (3.82±0.13%), the atherogenic index was 0.43. According to in vivo study results, it was shown that the introduction of developed product during 42 days into the diet of hyperlipidemic rats lead to a decrease in the relative content of saturated fatty acids by 21.1%(P<0.05), mainly due to palmitic fatty acid reduction by 42.0% (P<0.05) compared with the control. The observed modifications of serum fatty acid composition resulted in the reduction of atherogenic index by 43.3% (P<0.05). The revealed positive dynamics of lipid metabolism recovery in hyperlipidemic rats makes it possible to recommend the developed product as a component of diet therapy, concomitant to the main treatment, for persons with risk of cardiovascular diseases, in particular, due to dyslipidemias.

About the Authors

I. M. Chernukha
V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences
Russian Federation

Irina M. Chernukha — doctor of technical sciences, professor, leading research scientist of Experimental clinic — laboratory «Biologically active substances of an animal origin»

109316, Moscow, Talalikhina str., 26 



E. A. Kotenkova
V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences
Russian Federation

Elena A. Kotenkova — candidate of technical sciences, senior research scientist, Experimental clinic-laboratory «Biologically active substances of an animal origin»

109316, Moscow, Talalikhina str., 26

 



References

1. Tutelian, V.A., Khavinson, V.Kh., Ryzhak, G.A., Linkova, N.S. (2014). Short Peptides as Components of Nutrition: Molecular Bases of Gomeostasis Regulation. Advances in Current Biology, 134(3), 227–235. (in Russian)

2. Khavinson, V.H., Chalisova, N.I., Linkova, N.S., Khalimov, R.I., Nichik, T.E. (2015). The dependence of tissue-specific peptides activity on the number of amino acids in the peptides. Fundamental research, 2–3, 497– 503. (in Russian)

3. Hui., Y.H. (2012). Handbook of Meat and Meat Processing, 2nd ed. USA, Taylor & Francis Group. — 1000 p. ISBN 9781439836835.

4. Mine, Y., Shahidi, F. (2006). Nutraceutical Science and Technology (Book 4). Nutraceutical Proteins and Peptides in Health and Disease. USA: Taylor & Francis Group. — 688 p. ISBN 9780824753542

5. Lafarga, T., Hayes, M. (2014). Bioactive peptides from meat muscle and by-products: generation, functionality and application as functional ingredients. Meat science, 98(2), 227–239.

6. Udenigwe, C.C., Howard, A. (2013). Meat proteome as source of functional biopeptides. Food Research International, 54(1), 1021–1032.

7. Weiss, J, Gibis, M, Schuh, V, Salminen, H. (2010). Advances in ingredient and processing systems for meat and meat products. Meat Science, 86(1), 196–213.

8. Kochetkova, A.A., Vorobyova, V.M., Vorobyova, I.S., Sarkisyan, V.A., Zorina, E.E., Shatnyuk, L.N., Mikheeva, G.A., Yudina, A.V. (2016). Theoretical and Practical Aspects of the Specialized Food for Diet Therapy in Cardiovascular Diseases Development. Food Industry, 8, 8–12. (in Russian)

9. Fagerberg, L., Hallstrom, B.M., Oksvold, P., Kampf, C., Djureinovic, D., Odeberg, J., Habuka, M., Tahmasebpoor, S., Danielsson, A., Edlund, K., Asplund, A., Sjostedt, E., Lundberg, E., Szigyarto, C.A.-K., Skogs, M., Ottosson Takanen, J., Berling, H., Tegel, H., Mulder, J., Nilsson, P., Schwenk, J.M., Lindskog, C., Danielsson, F., Mardinoglu, A., Sivertsson, A., Von Feilitzen, K., Forsberg, M., Zwahlen, M., Olsson, I., Navani, S., Huss, M., Nielsen, J., Ponten, F., Uhlen, M. (2014). Analysis of the Human Tissuespecific Expression by Genome-wide Integration of Transcriptomics and Antibody-based Proteomics. Molecular and Cellular Proteomics, 13(2), 397–406.

10. Chugunov, A. O. (2010) Unknown peptides. Nauka i zhizn, 10, 26–32. (in Russian)

11. Сhernukha, I.M., Fedulova, L.V., Dydykin, A.S. (2014). Safe and useful products as the main factor determining the quality of life. Vsyo o myase, 2, 20–22. (in Russian)

12. Gladkikh, N.M., Fedulova, L.V. (2017). Biological value of canned minced meat specialized. Vsyo o myase, 3, 28–31. (in Russian)

13. Pogozheva, A.V. (2004). Fundamentals of rational diet therapy for cardiovascular diseases. Klinicheskaya ddietologiya, 2, 17–29. (in Russian)

14. Patieva, A.M., Patieva, S.V., Velichko, V.A. (2012). Fat-acid content of bacon of pigs of danish breed. Herald NGIEI, 8(15), 69–82. (in Russian)

15. Lisitsyn, A.B., Chernukha, I.M., Kotenkova, E.A., Fedulova, L.V. Sposob modelirovaniya ateroscleroza. Patent RF, no. 2524127. 2014 (in Russian)

16. Skurikhin, I. M., Tutelyan, V. A. (1998). Guide to methods of analysis of food quality and safety. M: Brandes-Medicine. –341 p. ISBN 5–225– 02777–6 (in Russian)

17. Lisitsyn, A.B., Ivankin, A.N., Neklyudov, A.D. (2002). Methods of practical biotechnology. M: VNIIMP. –402 p. (In Russian)

18. Ulbricht, T.L.V., Southgate, D.A.T. (1991) Coronary heart disease: seven dietary factors. The Lancet, 338(8773), 985–992.

19. Lisitsyn, A.B., Chernukha, I.M., Kuznetsova, T.G., Orlova, O.N., Mkrtichan, V.S. (2011). Chemical composition of meat: Reference tables of the General chemical, amino acid, fatty acid, vitamin, macro — and microelement compositions and food (energy and biological) value of meat. M: VNIIMP. — 104p. (in Russian)

20. Titov, V.N. (2012). High dietary content of palmitic fatty acid is the major cause of increase in low-density lipoprotein cholesterol and arrterial intima atheromatosis. Ateroskleroz i dislipidemii, 3(8), 48–57. (in Russian)


For citation:


Chernukha I.M., Kotenkova E.A. IFLUENCE OF FUNCTIONAL FOOD PRODUCT ON SERUM FATTY ACID COMPOSITION IN HYPERLIPIDEMIC RATS. Food systems. 2018;1(4):4-9. (In Russ.) https://doi.org/10.21323/2618-9771-2018-1-4-4-9

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ISSN 2618-9771 (Print)
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