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Glycation end products and technological aspects of reducing immunogenicity of specialized food products for nutrition of athletes

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Food allergy, which affects about 8% of children and 5% of adults in the world, is one of the major global health problems, and allergen control is an important aspect of food safety. According to the FALCPA (Food Allergen Labeling and Consumer Protection Act of 2004 FDA), more than 160 foods can cause allergic reactions, with eight of them responsible for 90% of all food allergies in the United States, including milk, eggs, wheat, peanuts, soybeans, tree nuts, crustaceans and fish, also known as the Big 8. Most foods that are sources of obligate allergens are heat treated before consumption, which can trigger the Maillard reaction, which produces glycation end products. Symptoms of food sensitization are known to significantly affect the quality of life, gut microbial diversity and adaptation potential. In particular, in athletes, this can be expressed in a decrease in the effectiveness of the training process, which leads to poor endurance and athletic performance. In this regard, it seems relevant to study the effect of the Maillard reaction and AGEs on the immunogenicity of proteins and the possible relationship between these compounds and food allergy, as well as to develop measures to prevent the adverse effect of allergens on the body of a professional athlete and any other consumer.

About the Authors

I. V. Kobelkova
Federal Research Center for Nutrition, Biotechnology and Food Safety; Academy of Postgraduate Education
Russian Federation

Irina V. Kobelkova, Candidate of Medical Sciences, Leading Researcher, Laboratory of Sports Anthropology and Nutritionology; Docent

Ustinsky pr., 2/14с1, 109240, Moscow
Volokolamsk Highway, 91, 125371, Moscow
Tel.: + 7–910–406–40–31

M. M. Korosteleva
Federal Research Center for Nutrition, Biotechnology and Food Safety; Peoples’ Friendship University of Russia
Russian Federation

Margarita M. Korosteleva, Candidate of Medical Sciences, Senior Researcher, Laboratory of Sports Anthropology and Nutritionology; Docent, Department of Nursing Management, Medical Institute

Ustinsky pr., 2/14с1, 109240, Moscow
Miklukho-Maclay str., 6, 117198, Moscow
Tel.: +7–985–567–78–22

D. B. Nikityuk
Federal Research Center for Nutrition, Biotechnology and Food Safety; I.M. Sechenov First Moscow State Medical University
Russian Federation

Dmitry B. Nikityuk, Doctor of Medical Sciences, Professor, Corresponding Member of the Russian Academy of Sciences, Director; Professor, Department of Operative Surgery and Topographic Anatomy

Ustinsky pr., 2/14с1, 109240, Moscow
Rossolimo str., 15/13(1), 119992, Moscow
Tel.: +7–495–695–53–60

M. S. Kobelkova
“Polyclinic No. 2” of the Administrative Department of the President of the Russian Federation
Russian Federation

Maria S. Kobelkova, Doctor

2nd Frunzenskaya street, 4, 119146, Moscow
Tel. +7–915–410–78–74


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For citation:

Kobelkova I.V., Korosteleva M.M., Nikityuk D.B., Kobelkova M.S. Glycation end products and technological aspects of reducing immunogenicity of specialized food products for nutrition of athletes. Food systems. 2021;4(4):278-285. (In Russ.)

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