Оценка антимикробных свойств водорастворимого экстракта из семян опунции индийской против бактериальных и грибковых патогенов

Увеличение проблемы возникновения устойчивости к противомикробным препаратам требует разработки альтернативных натуральных биоактивных соединений. В данной работе описывается определение антимикробной активности водорастворимых экстрактов из семян опунции индийской. Семена опунции индийской были собраны в регионе Бордж-Бу-Арреридж (Алжир). Были приготовлены водорастворимые экстракты и тестированы против отдельных штаммов бактерий и грибов, используя метод диффузии в агар. Были применены различные концентрации и измеряли зоны ингибирования для оценки антимикробной активности. Экстракт проявил низкую антибактериальную активность против определенных штаммов бактерий с ингибированием только при концентрации 110 мг/мл. Напротив, была зарегистрирована существенная противогрибковая активность против некоторых грибов и дрожжей с четкими зонами ингибирования. Результаты указывают на избирательный антимикробный эффект, что говорит о том, что биоактивные соединения, присутствующие в экстракте более активны против грибковых микроорганизмов, по сравнению с бактериями. Водорастворимые экстракты семян опунции индийской представляют собой потенциальный натуральный источник противогрибковых средств с ограниченным антибактериальным эффектом. Эти результаты поддерживают их потенциальное применение в рецептурах противогрибковых препаратов и стимулируют дальнейшие исследования для идентификации активных соединений и выяснения их механизмов действия.

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