foodsystFood systemsПищевые системы2618-97712618-7272Федеральный научный центр пищевых систем им. В.М. Горбатова РАН10.21323/2618-9771-2026-9-2-192-198foodsyst-1103Research ArticleСтатьиAntimicrobial evaluation of the hydro-soluble extract from opuntia ficus-indica seeds against bacterial and fungal pathogensОценка антимикробных свойств водорастворимого экстракта из семян опунции индийской против бактериальных и грибковых патогеновhttps://orcid.org/0000-0001-8152-2107СахрауиА.SakhraouiA.

Сахрауи Амира – PhD, Лаборатория характеристики и оценки природных ресурсов, кафедра пищевых наук

Эль-АнассерБордж-Бу-Арреридж, 34030 Бордж-бу-Арреридж

Amira Sakhraoui, PhD Food Sciences

El-Anasser Bordj Bou Arreridj 34030 Bordj Bou Arreridj

amira.sakhraoui@univ-bba.dzhttps://orcid.org/0000-0002-1110-6770ТуатиН.TouatiN.

Туати Нуреддин – PhD, адъюнкт-профессор,Лаборатория охраны здоровья и окружающей среды, кафедра пищевых наук

Эль-АнассерБордж-Бу-Арреридж, 34030 Бордж-бу-Арреридж

Noureddine Touati, PhD Food Sciences, Associate Professor, Laboratory of Health and Environment, Department of Food Sciences

El-Anasser Bordj Bou Arreridj 34030 Bordj Bou Arreridj

n.touati@univ-bba.dzhttps://orcid.org/0000-0002-3377-7866ХихатС.HihatS.

Хихат Сорайя – PhD, адъюнкт-профессор, кафедра пищевых наук

Эль-АнассерБордж-Бу-Арреридж, 34030 Бордж-бу-Арреридж

Soraya Hihat, PhD Food Sciences, Associate Professor, Department of Food Sciences

El-Anasser Bordj Bou Arreridj 34030 Bordj Bou Arreridj

soraya.hihat@univ-bba.dzhttps://orcid.org/0009-0003-1253-7753МадагБ.MadaghB.

Мадаг Билал – студент, Лаборатория охраны здоровья и окружающей среды, кафедра пищевых наук

Эль-АнассерБордж-Бу-Арреридж, 34030 Бордж-бу-Арреридж

Bilal Madagh, PhD Student Food Sciences, Laboratory of Health and Environment

El-Anasser Bordj Bou Arreridj 34030 Bordj Bou Arreridj

bilal.madagh@univ-bba.dzhttps://orcid.org/0000-0002-6372-8889БландоФ.BlandoF.

Бландо Федерика – адъюнкт-профессор

ул. Лечче-Монтерони, 73100 Лечче, Пулия

Federica Blando, Associate Professor

Via Provinciale Lecce-Monteroni – 73100 Lecce (LE) – Puglia

federica.blando@cnr.itЛаборатория характеристики и оценки природных ресурсов, кафедра пищевых наук, факультет биологии и естественных наук, Земли и Вселенной, Университет Мохаммеда Эль-Бахира Эль-Ибрахими в Бордж-Бу-АррериджеАлжирLaboratory of Characterization and Valorization of Natural Resources, University Mohamed El Bachir El Ibrahimi of Bordj Bou ArreridjAlgeriaЛаборатория охраны здоровья и окружающей среды, кафедра пищевых наук, факультет биологии и естественных наук, Земли и Вселенной, Университет Мохаммеда Эль-Бахира Эль-Ибрахими в Бордж-Бу-Арреридже; Кафедра пищевых наук, факультет биологии и естественных наук, Земли и Вселенной, Университет Мохаммеда Эль-Бахира Эль-Ибрахими в Бордж-Бу-АррериджеАлжирLaboratory of Health and Environment, University Mohamed El Bachir El Ibrahimi of Bordj Bou Arreridj; Faculty of Natural Science and Earth and Universe, University Mohamed El Bachir El Ibrahimi of Bordj Bou ArreridjAlgeriaКафедра пищевых наук, факультет биологии и естественных наук, Земли и Вселенной, Университет Мохаммеда Эль-Бахира Эль-Ибрахими в Бордж-Бу-Арреридже; Лаборатория биоматематики, биофизики, биохимии и наукометрии, Университет БеджайиАлжирFaculty of Natural Science and Earth and Universe, University Mohamed El Bachir El Ibrahimi of Bordj Bou Arreridj; Laboratory of Biomathematics Biophysic, Biochemical and Scientometry, University of BejaiaAlgeriaЛаборатория охраны здоровья и окружающей среды, кафедра пищевых наук, факультет биологии и естественных наук, Земли и Вселенной, Университет Мохаммеда Эль-Бахира Эль-Ибрахими в Бордж-Бу-АррериджеАлжирLaboratory of Health and Environment, University Mohamed El Bachir El Ibrahimi of Bordj Bou ArreridjAlgeriaИсследовательское подразделение в Лечче, Институт наук о производстве пищевых продуктов (ISPA), Национальный исследовательский совет (CNR)ИталияResearch Unit of Lecce, Institute of Sciences of Food Production (ISPA), National Research Council (CNR)Italy20260108202692192198Copyright © Sakhraoui A., Touati N., Hihat S., Madagh B., Blando F., 20262026Сахрауи А., Туати Н., Хихат С., Мадаг Б., Бландо Ф.Sakhraoui A., Touati N., Hihat S., Madagh B., Blando F.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.fsjour.com/jour/article/view/1103

The increasing emergence of antimicrobial resistance requires the development of alternative natural bioactive compounds. This research describes the evaluation of the antimicrobial activity of hydro-soluble extracts from Opuntia ficus-indica seeds. Seeds of Opuntia ficus-indica were collected from the Bordj Bou Arreridj region (Algeria). Hydro-soluble extracts were prepared and tested against selected bacterial and fungal strains using the disk diffusion method. Different concentrations were applied, and inhibition zones were measured to assess the antimicrobial activity. The extract exhibited low antibacterial activity, with inhibition observed only at 110 mg/mL against specific bacterial strains. In contrast, the significant antifungal activity was recorded, with clear inhibition zones against several fungi and yeasts. The results indicate a selective antimicrobial effect, suggesting that the bioactive compounds present in the extract are more active against fungal microorganisms than bacteria. Hydro-soluble extracts of Opuntia ficus-indica seeds constitute a potential natural source of antifungal agents with limited antibacterial effects. These findings support their potential application in antifungal formulations and encourage further studies to identify active compounds and elucidate their mechanisms of action.

Увеличение проблемы возникновения устойчивости к противомикробным препаратам требует разработки альтернативных натуральных биоактивных соединений. В данной работе описывается определение антимикробной активности водорастворимых экстрактов из семян опунции индийской. Семена опунции индийской были собраны в регионе Бордж-Бу-Арреридж (Алжир). Были приготовлены водорастворимые экстракты и тестированы против отдельных штаммов бактерий и грибов, используя метод диффузии в агар. Были применены различные концентрации и измеряли зоны ингибирования для оценки антимикробной активности. Экстракт проявил низкую антибактериальную активность против определенных штаммов бактерий с ингибированием только при концентрации 110 мг/мл. Напротив, была зарегистрирована существенная противогрибковая активность против некоторых грибов и дрожжей с четкими зонами ингибирования. Результаты указывают на избирательный антимикробный эффект, что говорит о том, что биоактивные соединения, присутствующие в экстракте более активны против грибковых микроорганизмов, по сравнению с бактериями. Водорастворимые экстракты семян опунции индийской представляют собой потенциальный натуральный источник противогрибковых средств с ограниченным антибактериальным эффектом. Эти результаты поддерживают их потенциальное применение в рецептурах противогрибковых препаратов и стимулируют дальнейшие исследования для идентификации активных соединений и выяснения их механизмов действия.

Опунция индийскаяводорастворимый экстрактантибактериальная активностьпротивогрибковая активностьпатогенные бактерииOpuntia ficus-indicahydro-soluble extractantibacterial activityantifungal activitypathogenic bacteriaДанная работа была финансирована Министерством высшего образования и научных исследований Алжира (грант на выполнение проекта PRFU № 00L01UN340120190001). Авторы благодарны Доктору Мехуху Насреддину за помощь в выполнении данной работы.This work was funded by the Algerian Ministry of Higher Education and Scientific Research (PRFU project grant № D00L01UN340120190001). Authors are grateful to Dr. Mekhoukh Nasreddine who helped us to carry out this work.ReferencesOgunnupebi, T.A., Oluyori, A.P., Dada, A.O., Oladeji, O.S., Adejumoke, A., Inyinbor, A.A., Egharevba, G.O. (2020). Promising natural products in crop protection and food preservation: Basis, advances, and future prospects. 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The authors declare that there are no conflicts of interest present.