Biochemical changes in rats after treatment with soft drink and menthol flavoured candy
https://doi.org/10.21323/2618-9771-2025-8-1-106-113
Abstract
The current study looked at the biochemical variations that occurred in rats after they were given menthol flavoured candies and soft drinks. Seventy male Wistar albino rats in total were acquired, split up into ten treatments of seven rats each, and treated with the following regimen for forty-two days. Group 1 is the control. Groups 2, 3, and 4 received 8, 5, and 2.5 ml of La Casera/kg body weight. Groups 5, 6, and 7 received 0.34, 0.22, and 0.11 g of Tom-Tom/kg body weight. The dosages for groups 8, 9, and 10 were 8, 5, and 2.5 ml of La Casera/kg body weight, as well as 0.34, 0.22, and 0.11 g of Tom-Tom/kg body weight correspondingly. The results showed that the groups given Tom-Tom and La Casera had lower levels of total protein (TP) and albumin (Alb), and significantly (p < 0.05) higher serum levels of alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase (ALP), total cholesterol (T-Chol), triacylglycerol (TAG), and low-density lipoprotein cholesterol (LDL–C). Furthermore, there was a substantial (p < 0.05) increase in the serum levels of TP, Alb, and ALT between groups 7 and 5. Prolonged use of Tom-Tom mixed with La Casera should be avoided due to the detrimental alterations in biochemical parameters and subsequent health repercussions.
About the Authors
E. F. IsojeNigeria
Endurance F. Isoje, PhD, Lecturer
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–803–950–73–71
I. O. Okoro
Nigeria
Israel O. Okoro, PhD, Senior Lecturer
P.M.B. 1, Abraka, Delta State
Tel.: +234–705–756–96–13
B. M. A. Ali
Russian Federation
Ali B. M. Ali, Doctor of Engineering, Vice Dean
56001, Karbala
Tel.: +964–9909–545–91–00
G. I. Edo
Nigeria
Great I. Edo, PhD, Lecturer
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–816–024–15–09
E. Yousif
Iraq
Emad Yousif, PhD, Professor
Al Jadriyah Bridge, 64074, Baghdad
Tel.: +964–770–583–93–00
J. Okpoghono
Nigeria
Joel Okpoghono, PhD, Lecturer
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–806–461–86–05
E. O. Okoro
Nigeria
Edith O. Okoro, Lecturer
P.M.B. 1, Abraka, Delta State
Tel.: +234–806–737–60–04
S. U. Okom
Nigeria
Solomon U. Okom, Assistant Lecturer
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–907–912 84–50
A. E. A. Essaghah
Nigeria
Arthur E. A. Essaghah, PhD, Professor
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–902–741–52–25
H. Umar
Cyprus
Huzaifa Umar, PhD, Senior Scientist
Near East Boulevard, 99138, Nicosia
Tel.: +357–9054–2888–84–19
J. O. Owheruo
Nigeria
Joseph O. Owheruo, PhD, Lecturer
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–806–524–07–37
P. O. Akpoghelie
Nigeria
Patrick O. Akpoghelie, PhD, Lecturer
P. M. B. 05, Ozoro-Kwale Road, Ozoro, Delta State
Tel.: +234–706–466–57–00
D. S. Ahmed
Russian Federation
Dina S. Ahmed, PhD, Lecturer
10074, Baghdad
Tel.: +964–770–613–17–92
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Review
For citations:
Isoje E.F., Okoro I.O., Ali B., Edo G.I., Yousif E., Okpoghono J., Okoro E.O., Okom S.U., Essaghah A.A., Umar H., Owheruo J.O., Akpoghelie P.O., Ahmed D.S. Biochemical changes in rats after treatment with soft drink and menthol flavoured candy. Food systems. 2025;8(1):106-113. https://doi.org/10.21323/2618-9771-2025-8-1-106-113