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<article article-type="review-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">foodsyst</journal-id><journal-title-group><journal-title xml:lang="en">Food systems</journal-title><trans-title-group xml:lang="ru"><trans-title>Пищевые системы</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2618-9771</issn><issn pub-type="epub">2618-7272</issn><publisher><publisher-name>Федеральный научный центр пищевых систем им. В.М. Горбатова РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21323/2618-9771-2025-8-3-407-413</article-id><article-id custom-type="elpub" pub-id-type="custom">foodsyst-859</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Valorization of citrus fruit wastes: Sustainable extraction of bioactive compounds for food and health applications</article-title><trans-title-group xml:lang="ru"><trans-title>Валоризация отходов переработки плодов цитрусовых: экологичная экстракция биоактивных соединений для применения в пищевых продуктах и улучшения здоровья</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9919-8760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аммар</surname><given-names>А. С. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Ammar</surname><given-names>A. S. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аммар Абдалла С. M. — профессор, Кафедра науки о питании, Сельскохозяйственный факультет</p><p>12613, Гиза, ул. Гамаа</p></bio><bio xml:lang="en"><p>Abdalla S.  M.  Ammar, Professor, Food Science Department, Faculty of Agriculture</p><p>Gamaa Street, Giza, 12613</p></bio><email xlink:type="simple">abdallaammar@agr.cu.edu.eg</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-1782-1599</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Рияд</surname><given-names>Ю. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Riyad</surname><given-names>Y. M.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Рияд Юсеф М. — профессор, Кафедра науки о питании, Сельскохозяйственный факультет</p><p>12613, Гиза, ул. Гамаа</p></bio><bio xml:lang="en"><p>Youssef M. Riyad, Professor, Food Science Department, Faculty of Agriculture</p><p>Gamaa Street, Giza, 12613</p></bio><email xlink:type="simple">yriyad74@yahoo.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0000-4421-4885</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Юнис</surname><given-names>М. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Younis</surname><given-names>M. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Юнис Мохамад И. — Ассистент преподавателя, Кафедра науки о питании, Сельскохозяйственный факультет</p><p>12613, Гиза, ул. Гамаа</p></bio><bio xml:lang="en"><p>Mohamed I. Younis, Teaching Assistant, Food Science Department, Faculty of Agriculture</p><p>Gamaa Street, Giza, 12613</p></bio><email xlink:type="simple">mohamedyounis2201@agr.cu.edu.eg</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-7399-1277</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Али</surname><given-names>М. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Ali</surname><given-names>M. R.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Али М. Р.  — адъюнкт-профессор, Кафедра науки о  питании, Сельскохозяйственный факультет</p><p>12613, Гиза, ул. Гамаа</p></bio><bio xml:lang="en"><p>Marwa R.  Ali, Associate Professor, Food Science Department, Faculty of Agriculture</p><p>Gamaa Street, Giza, 12613</p></bio><email xlink:type="simple">marwa3mrf@agr.cu.edu.eg</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Каирский университет</institution><country>Египет</country></aff><aff xml:lang="en"><institution>Cairo University</institution><country>Egypt</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>16</day><month>10</month><year>2025</year></pub-date><volume>8</volume><issue>3</issue><fpage>407</fpage><lpage>413</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ammar A.S., Riyad Y.M., Younis M.I., Ali M.R., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Аммар А.С., Рияд Ю.М., Юнис М.И., Али М.Р.</copyright-holder><copyright-holder xml:lang="en">Ammar A.S., Riyad Y.M., Younis M.I., Ali M.R.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.fsjour.com/jour/article/view/859">https://www.fsjour.com/jour/article/view/859</self-uri><abstract><p>Globally grown and handled citrus fruits produce a lot of by-products, including pulp, seeds, and peels. Often considered agroindustrial waste, rich in significant bioactives such as flavonoids, phenolic acids, limonoids, pectin, and essential oils, these materials are now considered attractive sustainable sources. This review explores recent developments in green extraction techniques, including ultrasonic-assisted, microwave-assisted, enzyme-assisted, supercritical fluid, pressurized liquid extraction, and natural deep eutectic solvents. Key parameters like solvent type, temperature, duration, and particle size are evaluated for their influence on yield and quality. Green methods provide better selectivity, scalability, and environmental benefits than traditional approaches. Citrus-derived compounds have promise in antimicrobial packaging and cosmetics beyond their application as nutritional supplements and food preservatives. Combining intelligent optimization techniques with circular biorefinery designs indicates a bright future for citrus waste valorization. The review emphasizes the change toward environmentally friendly technology for sustained value recovery despite difficulties in cost and regulation.</p></abstract><trans-abstract xml:lang="ru"><p>Во всем мире в результате выращивания и переработки плодов цитрусовых образуется большое количество побочных продуктов, таких как мякоть, семена и кожура. Зачастую рассматриваемые как отходы агро-промышленного производства, эти материалы, богатые важными биоактивными веществами, такими как флавоноиды, фенольные кислоты, пектин, лимоноиды, эфирные масла, в настоящее время считаются привлекательными экологичными источниками. В данном обзоре рассмотрены современные достижения в «зелёных» технологиях экстракции, включая ультразвуковую, микроволновую, ферментативную, суперкритическую флюидную экстракцию, жидкостную экстракцию под давлением, а также натуральные глубокие эвтектические растворители. Проведена оценка ключевых параметров, таких как тип растворителя, температура, продолжительность и размер частиц. «Зелёные» методы обеспечивают лучшей селективностью, масштабируемостью и пользой для окружащей среды по сравнению с традиционными подходами. Полученные из цитрусовых соединения обладают потенциалом применения в антимикробной упаковке и косметических средствах помимо их применения в качестве пищевых добавок и консервантов пищевых продуктов. Комбинирование интеллектуальных методов со схемами биопереработки замкнутого цикла означает светлое будущее для валоризации отходов переработки цитрусовых. Данный обзор сфокусирован на изменениях в направлении экологически безопасной технологии для устойчивого извлечения ценности несмотря на затруднения, связанные с затратами и законодательством.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>отходы цитрусовых</kwd><kwd>биоактивные соединения</kwd><kwd>«зелёная» экстракция</kwd><kwd>экологичная переработка</kwd><kwd>флавоноиды</kwd><kwd>пектин</kwd><kwd>экономика замкнутого цикла</kwd></kwd-group><kwd-group xml:lang="en"><kwd>citrus waste</kwd><kwd>bioactive compounds</kwd><kwd>green extraction</kwd><kwd>sustainable processing</kwd><kwd>flavonoids</kwd><kwd>pectin</kwd><kwd>circular economy</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Kato-Noguchi, H., Kato, M. (2025). Pesticidal activity of citrus fruits for the development of sustainable fruit-processing waste management and agricultural production. 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