foodsystFood systemsПищевые системы2618-97712618-7272Федеральный научный центр пищевых систем им. В.М. Горбатова РАН10.21323/2618-9771-2018-1-3-33-37foodsyst-17Research ArticleСтатьиALTERNATIVE METHODS OF BIOMODELING FOR FUNCTIONAL FOOD PRODUCTS EFFECTIVENESS RESEARCHПРИМЕНЕНИЕ АЛЬТЕРНАТИВНЫХ МЕТОДОВ БИОМОДЕЛИРОВАНИЯ ДЛЯ ИЗУЧЕНИЯ ЭФФЕКТИВНОСТИ ФУНКЦИОНАЛЬНЫХ ПРОДУКТОВ ПИТАНИЯФедуловаЛ. В.FedulovaLiliya V.

кандидат технических наук, заведующая, Экспериментальная клиника — лаборатория биологически активных веществ животного происхождения

109316, г. Москва, ул. Талалихина, 26. Тел.: +7–495–676–92–11

candidate of technical sciences, head of Experimental clinic-laboratory «Biologically active substances of an animal origin»

109316, Moscow, Talalikhina str., 26Tel.: +7–495–676–92–11

l.fedulova@fncps.ruВасилевскаяЕ. Р.VasilevskayaEkaterina R.

научный сотрудник, Экспериментальная клиника-лаборатория биологически активных веществ животного происхождения

109316, г. Москва, ул. Талалихина, 26. Тел.: +7–495–676–92–11

researcher, Experimental clinic — research laboratory of biologically active substances of an animal origin

109316, Moscow, Talalikhina str., 26Tel.: +7–495–676–92–11

e.vasilevskaya@fncps.ruКотенковаЕ. А.KotenkovaElena A.

кандидат технических наук, старший научный сотрудник, Экспериментальная клиника-лаборатория биологически активных веществ животного происхождения

109316, г. Москва, ул. Талалихина, 26. Тел.: +7–495–676–92–11

candidate of technical sciences, senior research scientist, Experimental clinic-laboratory «Biologically active substances of an animal origin»

109316, Moscow, Talalikhina str., 26Tel.: +7–495–676–92–11

e.kotenkova@fncps.ruКашиноваЭ. Б.KashinovaElta B.

кандидат технических наук, научный сотрудник, Экспериментальная клиника -лаборатория биологически активных веществ животного происхождения

109316, г. Москва, ул. Талалихина, 26. Тел.: +7–495–676–92–11

candidate of technical sciences, researcher, Experimental clinic — laboratory of biologically active substances of an animal origin

109316, Moscow, Talalikhina str., 26Tel.: +7–495–676–92–11

e.kashinova@fncps.ruФедеральный научный центр пищевых систем им. В.М. Горбатова РАН, МоскваРоссияV.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, MoscowRussian Federation201811102018133337Copyright © Fedulova L.V., Vasilevskaya E.R., Kotenkova E.A., Kashinova E.B., 20182018Федулова Л.В., Василевская Е.Р., Котенкова Е.А., Кашинова Э.Б.Fedulova L.V., Vasilevskaya E.R., Kotenkova E.A., Kashinova E.B.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.fsjour.com/jour/article/view/17

The article describes in vitro methods basic principles, authors analyzed cell and tissue cultures used to assess toxicity and specific biological activity, including metabolic processes, include antihypertensive and cytoprotective properties analysis, antioxidant activity (in vitro and ex vivo) used to study ingredients functional properties based on animal origin raw materials, as well as meat products.

В статье рассмотрены основные принципы методов in vitro, проанализированы применяемые культуры клеток и тканей, используемые для оценки токсичности и специфической биологической активности, включая исследования метаболических процессов, анализ гипотензивных и цитопротективных свойств, антиоксидантной активности (in vitro и ex vivo), используемые для оценки функциональных свойств ингредиентов на основе сырья животного происхождения, а также мясных продуктов.

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The authors declare that there are no conflicts of interest present.