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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">foodsyst</journal-id><journal-title-group><journal-title xml:lang="en">Food systems</journal-title><trans-title-group xml:lang="ru"><trans-title>Пищевые системы</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2618-9771</issn><issn pub-type="epub">2618-7272</issn><publisher><publisher-name>Федеральный научный центр пищевых систем им. В.М. Горбатова РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21323/2618-9771-2021-4-4-255-258</article-id><article-id custom-type="elpub" pub-id-type="custom">foodsyst-133</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>Juice nanotechnology: A mini review</article-title><trans-title-group xml:lang="ru"><trans-title>Нанотехнологии сока. Мини-обзор</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0002-9919-8760</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Аммар</surname><given-names>А. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Ammar</surname><given-names>A. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Аммар Абдалла С. — профессор, Кафедра науки о питании, Сельскохозяйственный факультет</p><p>12613, Гиза, ул. ГамааТел.: +2–0101–997–17–99</p></bio><bio xml:lang="en"><p>Abdalla S. Ammar, Professor, Department of Food Science, Faculty of Agriculture</p><p>Gamaa Street, Giza, 12613Tel.: +2–0101–997–17–99</p></bio><email xlink:type="simple">abdallaammar@agr.cu.edu.eg</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-4696-9848</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Базараа</surname><given-names>В. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bazaraa</surname><given-names>W. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Базараа Ваэль А. — профессор, Кафедра науки о питании, Сельскохозяйственный факультет</p><p>12613, Гиза, ул. ГамааТел.: +2–0100–415–49–49</p></bio><bio xml:lang="en"><p>Wael A. Bazaraa, Professor, Department of Food Science, Faculty of Agriculture</p><p>Gamaa Street, Giza, 12613Tel.: +2–0100–415–49–49</p></bio><email xlink:type="simple">waelbazaraa@agr.cu.edu.eg</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru">Каирский Университет<country>Египет</country></aff><aff xml:lang="en">Cairo University<country>Egypt</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2021</year></pub-date><pub-date pub-type="epub"><day>05</day><month>01</month><year>2022</year></pub-date><volume>4</volume><issue>4</issue><fpage>255</fpage><lpage>258</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Ammar A.S., Bazaraa W.A., 2022</copyright-statement><copyright-year>2022</copyright-year><copyright-holder xml:lang="ru">Аммар А.С., Базараа В.А.</copyright-holder><copyright-holder xml:lang="en">Ammar A.S., Bazaraa W.A.</copyright-holder><license license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.fsjour.com/jour/article/view/133">https://www.fsjour.com/jour/article/view/133</self-uri><abstract><p>In the past two decades, nano-science is widely used in different applications and the increased interest in the utilization of nanoparticles in food processing is clear. Such applications include processing, packaging, development of functional food, safety, foodborne pathogens detection, and shelf-life extension. In this article, the essential facts and the latest uses of nano-science in fruit and vegetable juices were described. The green synthesis of nanoparticles with antioxidant, antibacterial and antifungal characteristics is of great interest in food preservation. These nanoparticles such as metals, oxidized metals and its bioactivity in juice were reviewed. The current procedures to prepare nanojuice including nanofiltration and the most recent nanomilling were presented. Beside the preparation, special emphasis has also been given to the chemical as well as the biological (microbial and enzymatic) quality of the produced nanojuice. The role of nanotechnology in the development of the smart and the active food packaging systems for the improvement of food shelf- life and quality was also discussed. Since the physical and chemical characteristics of nanoparticles are completely different from those of macro-size. Therefore, special and urgent attention by responsible authorities should be given and effective policies should be applied for food products to ensure product quality, customer health and safety as well as the environmental protection.</p></abstract><trans-abstract xml:lang="ru"><p>В последние два десятилетия нанонаука широко используется в различных областях и очевиден повышенный интерес к применению наночастиц при переработке пищевых продуктов. Такие области включают переработку, упаковку, разработку функциональных продуктов, безопасность, обнаружение пищевых патогенов и продление сроков хранения. В данной статье описаны важнейшие факты и современное применение нанонауки для фруктовых и овощных соков. Большой интерес вызывает зеленый синтез наночастиц с антиоксидантными, антибактериальными и противогрибковыми свойствами для увеличения сроков хранения пищевых продуктов. Сделан обзор наночастиц, таких как металлы, некоторых видов их оксидов и окислов, и их биологическая активность в соке. Приведены современные процедуры для производства нано-соков, включая нано-фильтрацию и самое современное нано-измельчение. Помимо производства, особый акцент в обзоре сделан на химических, а также биологических (микробиологических и ферментативных) качественных характеристиках произведенных нано-соков. Также обсуждена роль нано-технологии в развитии систем «разумной» и активной упаковки для увеличения сроков хранения и улучшения качества пищевых продуктов. Показано, что физические и химические характеристики наночастиц полностью отличаются от характеристик частиц макроразмера. Сделан вывод о том, что производителям пищевой продукции при использовании новых технологий должно уделяться особое внимание обеспечению ее качества для сохранения доверия потребителей. При этом контролирующими и регулирующими организациями должна проводится эффективная политика по обеспечению безопасности пищевой продукции, сохранности здоровья потребителей и защиты окружающей среды.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>зеленый синтез</kwd><kwd>нано-сок</kwd><kwd>нано-измельчение</kwd><kwd>нано-фильтрация</kwd><kwd>нано-упаковка</kwd><kwd>регулирование</kwd></kwd-group><kwd-group xml:lang="en"><kwd>green synthesis</kwd><kwd>nanojuice</kwd><kwd>nanomilling</kwd><kwd>nanofiltration</kwd><kwd>nanopackaging</kwd><kwd>regulation</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Bajpai, V. K., Kamle, M., Shukla, S., Mahato, D. K., Chandra, P., Hwang, S. K. et al. (2018). Prospects of using nanotechnology for food preservation, safety and security. Journal of Food and Drug Analysis, 26(4), 1201–1214. https://doi.org/10.1016/j.jfda.2018.06.011</mixed-citation><mixed-citation xml:lang="en">Bajpai, V. K., Kamle, M., Shukla, S., Mahato, D. K., Chandra, P., Hwang, S. K. et al. (2018). Prospects of using nanotechnology for food preservation, safety and security. Journal of Food and Drug Analysis, 26(4), 1201–1214. https://doi.org/10.1016/j.jfda.2018.06.011</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Peters, R. J. B., Bouwmeester, H., Gottardo, S., Amenta, V., Arena, M., Brandhoff, P. et al. (2016). Nanomaterials for products and application in agriculture, feed and food. Trends in Food Science and Technology, 54, 155–164. https://doi.org/10.1016/j.tifs.2016.06.008</mixed-citation><mixed-citation xml:lang="en">Peters, R. J. B., Bouwmeester, H., Gottardo, S., Amenta, V., Arena, M., Brandhoff, P. et al. (2016). Nanomaterials for products and application in agriculture, feed and food. Trends in Food Science and Technology, 54, 155–164. https://doi.org/10.1016/j.tifs.2016.06.008</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Berekaa, M.M. (2015). Nanotechnology in food industry; advances in food processing, packaging and food safety. International Journal of Current Microbiology and Applied Sciences, 4(5), 345–357.</mixed-citation><mixed-citation xml:lang="en">Berekaa, M.M. (2015). Nanotechnology in food industry; advances in food processing, packaging and food safety. International Journal of Current Microbiology and Applied Sciences, 4(5), 345–357.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Mousavi, S.R., Rezaei, M. (2011). Nanotechnology in Agriculture and Food Production. Journal of Applied Environmental and Biological Science, 1(10), 414–419.</mixed-citation><mixed-citation xml:lang="en">Mousavi, S.R., Rezaei, M. (2011). Nanotechnology in Agriculture and Food Production. Journal of Applied Environmental and Biological Science, 1(10), 414–419.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Gilligan, B.K. (2008). Nanny, Nano, Boo, Boo Food? Retrieved from http://www.towerofbabel.com/blog/2008/08/28/nanny-nano-boo-boofood/. Accessed September 05, 2021</mixed-citation><mixed-citation xml:lang="en">Gilligan, B.K. (2008). Nanny, Nano, Boo, Boo Food? Retrieved from http://www.towerofbabel.com/blog/2008/08/28/nanny-nano-boo-boofood/. Accessed September 05, 2021</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L. at al. (2008). Applications and implications of nanotechnologies for the food sector. Food Additives and Contaminants — Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 25(3), 241–258. https://doi.org/10.1080/02652030701744538</mixed-citation><mixed-citation xml:lang="en">Chaudhry, Q., Scotter, M., Blackburn, J., Ross, B., Boxall, A., Castle, L. at al. (2008). Applications and implications of nanotechnologies for the food sector. Food Additives and Contaminants — Part A Chemistry, Analysis, Control, Exposure and Risk Assessment, 25(3), 241–258. https://doi.org/10.1080/02652030701744538</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Chaudhry, Q., Castle, L., Watkins, R. (2010). Nanotechnologies in Food. Royal Society of Chemistry Publishers, Cambridge, UK. https://doi.org/10.1039/9781847559883</mixed-citation><mixed-citation xml:lang="en">Chaudhry, Q., Castle, L., Watkins, R. (2010). Nanotechnologies in Food. Royal Society of Chemistry Publishers, Cambridge, UK. https://doi.org/10.1039/9781847559883</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Momin, J.K., Jayakumar, C., Prajapati, J.B. (2013). Potential of nanotechnology in functional foods. Emirates Journal of Food and Agriculture, 25(1), 10–19. https://doi.org/10.9755/ejfa.v25i1.9368</mixed-citation><mixed-citation xml:lang="en">Momin, J.K., Jayakumar, C., Prajapati, J.B. (2013). Potential of nanotechnology in functional foods. Emirates Journal of Food and Agriculture, 25(1), 10–19. https://doi.org/10.9755/ejfa.v25i1.9368</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Mohsen, S.M., Ammar, A.S.M., El-Amry, H.G., Abd El-Salam, R.S. (2020). Nano polyphenols and nano tocopherols from wheat bran extract. Singapore Journal of Scientific Research, 10(1), 16–22. https://doi.org/10.3923/sjsres.2020.16.22</mixed-citation><mixed-citation xml:lang="en">Mohsen, S.M., Ammar, A.S.M., El-Amry, H.G., Abd El-Salam, R.S. (2020). Nano polyphenols and nano tocopherols from wheat bran extract. Singapore Journal of Scientific Research, 10(1), 16–22. https://doi.org/10.3923/sjsres.2020.16.22</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">Arend, G.D., Rezzadori, K., Soares, L.S., Petrus, J.C.C. (2019). Performance of nanofiltration process during concentration of strawberry juice. Journal of Food Science and Technology, 56(4), 2312–2319. https://doi.org/10.1007/s13197–019–03659-z</mixed-citation><mixed-citation xml:lang="en">Arend, G.D., Rezzadori, K., Soares, L.S., Petrus, J.C.C. (2019). Performance of nanofiltration process during concentration of strawberry juice. Journal of Food Science and Technology, 56(4), 2312–2319. https://doi.org/10.1007/s13197–019–03659-z</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Vivekanand, V., Iyer, M., Ajlouni, S. (2012). Clarification and stability enhancement of pear juice using loose nanofiltration. Journal of Food Processing and Technology, 3(6), Article 1000162. https://doi.org/10.4172/2157–7110.1000162</mixed-citation><mixed-citation xml:lang="en">Vivekanand, V., Iyer, M., Ajlouni, S. (2012). Clarification and stability enhancement of pear juice using loose nanofiltration. Journal of Food Processing and Technology, 3(6), Article 1000162. https://doi.org/10.4172/2157–7110.1000162</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Carrín, M. E., Buglione, M. B., Lozano, J. E. (16–20 September 2007). Removal of dark compounds from fruit juices by membrane separation. Proceedings of European Congress of Chemical Engineering (ECCE-6) Copenhagen, 2007.</mixed-citation><mixed-citation xml:lang="en">Carrín, M. E., Buglione, M. B., Lozano, J. E. (16–20 September 2007). Removal of dark compounds from fruit juices by membrane separation. Proceedings of European Congress of Chemical Engineering (ECCE-6) Copenhagen, 2007.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Li, C., Ma, Y., Li, H., Peng, G. (2019). Exploring the nanofiltration mass transfer characteristic and concentrate process of procyanidins from grape juice. Food Science and Nutrition, 7(5), 1884–1890. https://doi.org/10.1002/fsn3.1045</mixed-citation><mixed-citation xml:lang="en">Li, C., Ma, Y., Li, H., Peng, G. (2019). Exploring the nanofiltration mass transfer characteristic and concentrate process of procyanidins from grape juice. Food Science and Nutrition, 7(5), 1884–1890. https://doi.org/10.1002/fsn3.1045</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">Kong, C. S., Lee, S. H., Seo, J. O., Park, K.Y., Rhee, S. H. (2006). Anti-adipogenic effect of Dongchimi nano juice in mouse 3T3-L1 adipocytes. Journal of Food Science and Nutrition, 11(4), 285–288. https://doi.org/10.3746/jfn.2006.11.4.285</mixed-citation><mixed-citation xml:lang="en">Kong, C. S., Lee, S. H., Seo, J. O., Park, K.Y., Rhee, S. H. (2006). Anti-adipogenic effect of Dongchimi nano juice in mouse 3T3-L1 adipocytes. Journal of Food Science and Nutrition, 11(4), 285–288. https://doi.org/10.3746/jfn.2006.11.4.285</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">Bazaraa, W.A., Ammar, A.S., Aqlan, A.M. (2020). Effects of kiwi’s pectin methylesterase inhibitor, nanomilling and pasteurization on orange juice quality. Food Science and Nutrition, 8(12), 6367–6379. https://doi.org/10.1002/fsn3.1886</mixed-citation><mixed-citation xml:lang="en">Bazaraa, W.A., Ammar, A.S., Aqlan, A.M. (2020). Effects of kiwi’s pectin methylesterase inhibitor, nanomilling and pasteurization on orange juice quality. Food Science and Nutrition, 8(12), 6367–6379. https://doi.org/10.1002/fsn3.1886</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Warczok, J. Ferrando, M. Lopez, F., Guell, C. (2004). Concentration of apple and pear juices by nanofiltration at low pressures. Journal of Food Engineering, 63(1), 63–70. https://doi.org/10.1016/S0260–8774(03)00283–8</mixed-citation><mixed-citation xml:lang="en">Warczok, J. Ferrando, M. Lopez, F., Guell, C. (2004). Concentration of apple and pear juices by nanofiltration at low pressures. Journal of Food Engineering, 63(1), 63–70. https://doi.org/10.1016/S0260–8774(03)00283–8</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">Dawale, S.A., Jawade, N.R. (2014). Using nanofiltration and ultrafiltration for the concentration of Amla (Phyllanthus Emblica) Juice. International Journal of NanoScience and Nanotechnology, 5(1), 59–65.</mixed-citation><mixed-citation xml:lang="en">Dawale, S.A., Jawade, N.R. (2014). Using nanofiltration and ultrafiltration for the concentration of Amla (Phyllanthus Emblica) Juice. International Journal of NanoScience and Nanotechnology, 5(1), 59–65.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Pruksasri, S., Lanner, B., Novalin, S. (2020). Nanofiltration as a potential process for the reduction of sugar in apple juices on an industrial scale. LWT, 133, Article 110118. https://doi.org/10.1016/j.lwt.2020.110118</mixed-citation><mixed-citation xml:lang="en">Pruksasri, S., Lanner, B., Novalin, S. (2020). Nanofiltration as a potential process for the reduction of sugar in apple juices on an industrial scale. LWT, 133, Article 110118. https://doi.org/10.1016/j.lwt.2020.110118</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Patil, S., Hosapete, S., Irkal, S., Rajput, S. (2019). Synthesis and characterization of zirconium nano particles from orange juice and orange peel. Journal of Applied Chemistry (IOSR-JAC,) 12(7 Ser.I), 29–37. https://doi.org/10.9790/5736–1207012937</mixed-citation><mixed-citation xml:lang="en">Patil, S., Hosapete, S., Irkal, S., Rajput, S. (2019). Synthesis and characterization of zirconium nano particles from orange juice and orange peel. Journal of Applied Chemistry (IOSR-JAC,) 12(7 Ser.I), 29–37. https://doi.org/10.9790/5736–1207012937</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Jackson, T.C., Uwah, T.O., Ifekpolugo, N.L., Emmanuel, N.A. (2018). Comparison of antimicrobial activities of Silver nanoparticles biosynthesized from some citrus species. American Journal of Nano Research and Applications, 6(2), 54–59. https://doi.org/10.11648/j.nano.20180602.12</mixed-citation><mixed-citation xml:lang="en">Jackson, T.C., Uwah, T.O., Ifekpolugo, N.L., Emmanuel, N.A. (2018). Comparison of antimicrobial activities of Silver nanoparticles biosynthesized from some citrus species. American Journal of Nano Research and Applications, 6(2), 54–59. https://doi.org/10.11648/j.nano.20180602.12</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Silwana, N., Calderón, B., Ntwampe, S., Fullana, A. (2020). Heterogeneous fenton degradation of patulin in apple juice using carbon-encapsulated nano zero-valent iron (CE-nZVI). Foods, 9, Article foods9050674. https://doi.org/10.3390/foods9050674</mixed-citation><mixed-citation xml:lang="en">Silwana, N., Calderón, B., Ntwampe, S., Fullana, A. (2020). Heterogeneous fenton degradation of patulin in apple juice using carbon-encapsulated nano zero-valent iron (CE-nZVI). Foods, 9, Article foods9050674. https://doi.org/10.3390/foods9050674</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Sachko, A., Kobasa, I., Moysyura, O., Vorobets, M. (2020). Efficiency of apple juice clarification with using of nano-sized mineral oxides. Ukrainian Food Technology, 9(2), 361–372. https://doi.org/10.24263/2304-974X-2020–9–2–8</mixed-citation><mixed-citation xml:lang="en">Sachko, A., Kobasa, I., Moysyura, O., Vorobets, M. (2020). Efficiency of apple juice clarification with using of nano-sized mineral oxides. Ukrainian Food Technology, 9(2), 361–372. https://doi.org/10.24263/2304-974X-2020–9–2–8</mixed-citation></citation-alternatives></ref><ref id="cit23"><label>23</label><citation-alternatives><mixed-citation xml:lang="ru">EFSA. (2009). The potential risks arising from nanoscience and nanotechnologies on food and feed safety. The EFSA Journal, 7(3), 1–39. https://doi.org/10.2903/j.efsa.2009.958</mixed-citation><mixed-citation xml:lang="en">EFSA. (2009). The potential risks arising from nanoscience and nanotechnologies on food and feed safety. The EFSA Journal, 7(3), 1–39. https://doi.org/10.2903/j.efsa.2009.958</mixed-citation></citation-alternatives></ref><ref id="cit24"><label>24</label><citation-alternatives><mixed-citation xml:lang="ru">Mihindukulasuriya, S. D. F., Lim, L. T. (2014). Nanotechnology development in food packaging: a review. Trends in Food Science and Technology, 40(2), 149–167. https://doi.org/10.1016/j.tifs.2014.09.009</mixed-citation><mixed-citation xml:lang="en">Mihindukulasuriya, S. D. F., Lim, L. T. (2014). Nanotechnology development in food packaging: a review. Trends in Food Science and Technology, 40(2), 149–167. https://doi.org/10.1016/j.tifs.2014.09.009</mixed-citation></citation-alternatives></ref><ref id="cit25"><label>25</label><citation-alternatives><mixed-citation xml:lang="ru">He, X., Deng, H., Hwang, H. M. (2019).The current application of nanotechnology in food and agriculture. Journal of Food and Drug Analysis, 27(1), 1–21. https://doi.org/10.1016/J.JFDA.2018.12.002</mixed-citation><mixed-citation xml:lang="en">He, X., Deng, H., Hwang, H. M. (2019).The current application of nanotechnology in food and agriculture. Journal of Food and Drug Analysis, 27(1), 1–21. https://doi.org/10.1016/J.JFDA.2018.12.002</mixed-citation></citation-alternatives></ref><ref id="cit26"><label>26</label><citation-alternatives><mixed-citation xml:lang="ru">Nile, S., H., Baskar, V., Selvaraj, D., Nile, A., Xiao, J., Kai, G. (2020). Nanotechnologies in food science: applications, recent trends, and future perspectives. Nano-Micro Letters, 12(1), Article 45. https://doi.org/10.1007/s40820–020–0383–9</mixed-citation><mixed-citation xml:lang="en">Nile, S., H., Baskar, V., Selvaraj, D., Nile, A., Xiao, J., Kai, G. (2020). Nanotechnologies in food science: applications, recent trends, and future perspectives. Nano-Micro Letters, 12(1), Article 45. https://doi.org/10.1007/s40820–020–0383–9</mixed-citation></citation-alternatives></ref><ref id="cit27"><label>27</label><citation-alternatives><mixed-citation xml:lang="ru">Emamifar, A., Kadivar, M., Shahedi, M., Soleimanian-Zad, S. (2010). Evaluation of nanocomposite packaging containing Ag and ZnO on shelf life of fresh orange juice. Innovative Food Science and Emerging Technologies, 11(4), 742–748. https://doi.org/10.1016/j.ifset.2010.06.003</mixed-citation><mixed-citation xml:lang="en">Emamifar, A., Kadivar, M., Shahedi, M., Soleimanian-Zad, S. (2010). Evaluation of nanocomposite packaging containing Ag and ZnO on shelf life of fresh orange juice. Innovative Food Science and Emerging Technologies, 11(4), 742–748. https://doi.org/10.1016/j.ifset.2010.06.003</mixed-citation></citation-alternatives></ref><ref id="cit28"><label>28</label><citation-alternatives><mixed-citation xml:lang="ru">Singh, T., Shukla, S., Kumar, P., Wahla, V., Bajpai, V.K. (2017). Application of nanotechnology in food science: perception and overview. Frontiers in Microbiology, 8(AUG), Article 1501. https://doi.org/10.3389/fmicb.2017.01501</mixed-citation><mixed-citation xml:lang="en">Singh, T., Shukla, S., Kumar, P., Wahla, V., Bajpai, V.K. (2017). Application of nanotechnology in food science: perception and overview. Frontiers in Microbiology, 8(AUG), Article 1501. https://doi.org/10.3389/fmicb.2017.01501</mixed-citation></citation-alternatives></ref><ref id="cit29"><label>29</label><citation-alternatives><mixed-citation xml:lang="ru">Jain, A., Ranjan, S., Dasgupta, N., Ramalingam C. (2016). Nanomaterials in food and agriculture: an overview on their safety concerns and regulatory issues. Critical Reviews in Food Science and Nutrition, 58(2), 297–317. https://doi.org/10.1080/10408398.2016.1160363</mixed-citation><mixed-citation xml:lang="en">Jain, A., Ranjan, S., Dasgupta, N., Ramalingam C. (2016). Nanomaterials in food and agriculture: an overview on their safety concerns and regulatory issues. Critical Reviews in Food Science and Nutrition, 58(2), 297–317. https://doi.org/10.1080/10408398.2016.1160363</mixed-citation></citation-alternatives></ref><ref id="cit30"><label>30</label><citation-alternatives><mixed-citation xml:lang="ru">Savolainen, K., Pylkkänen, L., Norppa, H., Falck, G., Lindberg, H., Tuomi, T. et al. (2010). Nanotechnologies, engineered nanomaterials and occupational health and safety — A review. Safety Science, 48(8), 957–963. https://doi.org/10.1016/j.ssci.2010.03.006</mixed-citation><mixed-citation xml:lang="en">Savolainen, K., Pylkkänen, L., Norppa, H., Falck, G., Lindberg, H., Tuomi, T. et al. (2010). Nanotechnologies, engineered nanomaterials and occupational health and safety — A review. Safety Science, 48(8), 957–963. https://doi.org/10.1016/j.ssci.2010.03.006</mixed-citation></citation-alternatives></ref><ref id="cit31"><label>31</label><citation-alternatives><mixed-citation xml:lang="ru">Mahler, G. J., Esch, M. B., Tako, E., Southard, T. L., Archer, S. D., Glahn, R. P. et al. (2012). Oral exposure to polystyrene nanoparticles affects iron absorption. Nature Nanotechnology, 7(4), 264–271. https://doi.org/10.1038/nnano.2012.3</mixed-citation><mixed-citation xml:lang="en">Mahler, G. J., Esch, M. B., Tako, E., Southard, T. L., Archer, S. D., Glahn, R. P. et al. (2012). Oral exposure to polystyrene nanoparticles affects iron absorption. Nature Nanotechnology, 7(4), 264–271. https://doi.org/10.1038/nnano.2012.3</mixed-citation></citation-alternatives></ref><ref id="cit32"><label>32</label><citation-alternatives><mixed-citation xml:lang="ru">EC258–97 (1997). Regulation (EC) No. 258/97 of the European Parliament and of the Council concerning novel foods and novel food ingredients. CELEX-EUR Official Journal L 43, 14 February 1997, pp. 1–7. Retrieved from https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A31997R0258 Accesed: 15.09.2021.</mixed-citation><mixed-citation xml:lang="en">EC258–97 (1997). Regulation (EC) No. 258/97 of the European Parliament and of the Council concerning novel foods and novel food ingredients. CELEX-EUR Official Journal L 43, 14 February 1997, pp. 1–7. Retrieved from https://eur-lex.europa.eu/legal-content/EN/TXT/?uri=celex%3A31997R0258 Accesed: 15.09.2021.</mixed-citation></citation-alternatives></ref><ref id="cit33"><label>33</label><citation-alternatives><mixed-citation xml:lang="ru">Brien, N.O., Cummins, E. (2010). Ranking initial environmental and human health risk resulting from environmentally relevant nanomaterials. Journal of Environmental Science and Health — Part A Toxic/ Hazardous Substances and Environmental Engineering, 45(8), 992–1007. https://doi.org/10.1080/10934521003772410</mixed-citation><mixed-citation xml:lang="en">Brien, N.O., Cummins, E. (2010). Ranking initial environmental and human health risk resulting from environmentally relevant nanomaterials. Journal of Environmental Science and Health — Part A Toxic/ Hazardous Substances and Environmental Engineering, 45(8), 992–1007. https://doi.org/10.1080/10934521003772410</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
