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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">foodsyst</journal-id><journal-title-group><journal-title xml:lang="en">Food systems</journal-title><trans-title-group xml:lang="ru"><trans-title>Пищевые системы</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2618-9771</issn><issn pub-type="epub">2618-7272</issn><publisher><publisher-name>Федеральный научный центр пищевых систем им. В.М. Горбатова РАН</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.21323/2618-9771-2018-1-2-21-28</article-id><article-id custom-type="elpub" pub-id-type="custom">foodsyst-10</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>Статьи</subject></subj-group></article-categories><title-group><article-title>THEORETICAL SUBSTANTIATION OF DIRECT TRANSPORT OF BIOLOGICALLY ACTIVE COMPONENTS  IN CONDITIONS  OF MODELED GASTROINTESTINAL TRACT</article-title><trans-title-group xml:lang="ru"><trans-title>ТЕОРЕТИЧЕСКОЕ ОБОСНОВАНИЕ НАПРАВЛЕННОГО ТРАНСПОРТА БИОЛОГИЧЕСКИ АКТИВНЫХ КОМПОНЕНТОВ В УСЛОВИЯХ МОДЕЛИРУЕМОГО ЖЕЛУДОЧНО-КИШЕЧНОГО ТРАКТА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Евтеев</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Evteev</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>ведущий специалист учебно-научно-испытательной лабораторией по определению качества пищевой и сельскохозяйственной продукции</p></bio><bio xml:lang="en"><p>Head Researcher of the Laboratory of Quality Determination of Foods and Agricultural Products</p></bio><email xlink:type="simple">ewteew@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Горбунова</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Gorbunova</surname><given-names>N. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>аспирант кафедры «Технологии продуктов питания»</p></bio><bio xml:lang="en"><p>Post-graduate Student of the department «Technologies of Foodstuffs»</p></bio><email xlink:type="simple">gelladriel@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ларионова</surname><given-names>О. С.</given-names></name><name name-style="western" xml:lang="en"><surname>Larionova</surname><given-names>O. S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор биологических наук, доцент, заведующий кафедрой микробиологии, биотехнологии и химии</p></bio><bio xml:lang="en"><p>Doctor of Biological Sciences, Head of the department of microbiology, biotechnology and chemistry</p></bio><email xlink:type="simple">larionova1@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Банникова</surname><given-names>А. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Bannikova</surname><given-names>A. V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>доктор технических наук, директор Института международных образовательных программ, доцент кафедры «Технологии продуктов питания»</p></bio><bio xml:lang="en"><p>Doctor of technical Sciences, Director of the Institute of International Educational Programs, Docent of the department «Technologies of Foodstuffs»</p></bio><email xlink:type="simple">annbannikova@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>Саратовский государственный аграрный университет имени Н.И. Вавилова</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saratov State Agrarian University named after N.I. Vavilov</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2018</year></pub-date><pub-date pub-type="epub"><day>11</day><month>07</month><year>2018</year></pub-date><volume>1</volume><issue>2</issue><fpage>21</fpage><lpage>28</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Evteev A.V., Gorbunova N.V., Larionova O.S., Bannikova A.V., 2018</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="ru">Евтеев А.В., Горбунова Н.В., Ларионова О.С., Банникова А.В.</copyright-holder><copyright-holder xml:lang="en">Evteev A.V., Gorbunova N.V., Larionova O.S., Bannikova A.V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.fsjour.com/jour/article/view/10">https://www.fsjour.com/jour/article/view/10</self-uri><abstract><p>In this paper, the results of studies on the release of biological active compounds from their encapsulated forms under conditions of enzymatic hydrolysis in vitro are presented. In the phase of the model «small intestine» swelling of the capsules and their subsequent decay occurs, which allows to speak about the controlled release of encapsulated bioactive components. It was revealed that almost 90 % of the residual quantity of essential ingredients was released from the capsules in the model phase of the artificial «small intestine». At the end of the experiment, the capsules released all the encapsulated biologically active substances, regardless of the content of fish oil and phenolic compounds in them. It was noted that the poly-capsules had the greatest propensity to withstand the aggressive environment of the «model stomach» and concentrate in themselves the maximum amount of biologically active substances. Mathematical modeling confirms the direct transport of biologically active compounds and the role of the swelling of capsules in the release of biologically active compounds. two mathematical models describing the classical theory of diffusion from capsules and incorporating the material relaxation coefficient demonstrate a combination of empirical and theoretical approaches in controlling the properties of encapsulated biologically active substances. the obtained data are promising in the field of development of improved and functional food products, as well as the dry ingredients and concentrates  </p></abstract><trans-abstract xml:lang="ru"><p>В работе приведены результаты исследований по изучению высвобождения биологических активных соединений из их инкапсулированных форм в условиях ферментативного гидролиза in vitro. В фазе модельного «кишечника» происходит набухание капсул и их последующий распад, что позволяет говорить о контролируемом высвобождении инкапсулированных биоактивных компонентов. Выявлено, что почти 90% от остаточного количества эссенциальных ингредиентов было высвобождено из капсул в модельной фазе «искусственного кишечника». В конце эксперимента капсулы высвобождали все инкапсулированные биологически активные вещества, независимо от содержания в них рыбьего жира и фенольных соединений.Отмечено, что полислойные капсулы имели наибольшую склонность противостоять агрессивной среде «модельного желудка» и сконцентрировать в себе максимальное количество биологически активных веществ. Математическое моделирование подтверждает направленный транспорт биологически активных соединений и роль набухания капсул в высвобождении биологически активных соединений. Две математические модели, описывающие классическую теорию диффузии из капсул и с включением коэффициента релаксации материалов, демонстрируют комбинацию эмпирического и теоретического подходов в управлении свойств инкапсулированных биологически активных веществ. Полученные данные перспективны в области разработки улучшенных и функциональных продуктов питания, а также сухих ингредиентов и концентратов.</p><p> </p></trans-abstract><kwd-group xml:lang="ru"><kwd>инкапсуляция</kwd><kwd>биологически  активные соединения</kwd><kwd>контролируемое высвобождение</kwd><kwd>ферментативный гидролиз</kwd></kwd-group><kwd-group xml:lang="en"><kwd>encapsulation</kwd><kwd>biologically active  substances</kwd><kwd>enzymatic hydrolysis</kwd><kwd>controlled release</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Горбунова, Н.В., Банникова, А.В. (2016). 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